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diagnosis rheumatology differential erythematosus symptoms management syndrome hematology msk oncology classification criteria disease pain pathophysiology testing vasculitis activation algorithm anesthesia
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and ... Associated with Joint ... Cytoid bodies (retinal ... Neurologic system ... system • Mitral
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... in small joints ... #SLE #systemic ... erythematosus #signs
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders ... of Lumbar Spine and ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... - Arthralgia, Arthritis ... #Lupus #Erythematosus ... pathophysiology #signs
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Lyme), reactive arthritis ... Chronic = RA, SLE ... , psoriatic arthritis ... rheumatology #approach #workup
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Antinuclear Antibody (ANA ... cytopenias) A Arthritis ... R Renal Disease ... #IMDAMNSHARP #sle ... #systemic #lupus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... in at least 2 joints ... low C4, Low C3 and ... Classification #Criteria #SLE ... #Systemic #Lupus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... Auto-Antibodies: - ANA ... #Systemic #Lupus ... autoantibodies #signs
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... : - ANA > ... months to years) Systemic ... • Immunologic Workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... : • Joint pain ... arthropathy • 90% joints ... APLA/LAC: • Renal ... #Systemic #Lupus
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