24 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... #SLE #systemic ... erythematosus #signs
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Workup Algorithm ... clinical context and signs ... Abdominal compartment syndrome ... syndrome: troponin ... #Workup #Algorithm
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
) - Differential ... • Hepatorenal syndromes ... Drugs • Emboli Systemic ... IgA, post-strep, lupus ... legionella) • Immune (lupus
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential ... inhibitors, hepatorenal syndrome ... Secondary GNs: Due to systemic ... Post-infectious GN, Lupus
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Chronic ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
antiphospholipid syndrome ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... Mnemonic #diagnosis #differential ... #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Dermatomyositis Erythema chronicum ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #skin #rashes #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... APLA/LAC: • Renal ... : • Chronic B-cell ... #Systemic #Lupus
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... B-cell lymphomas), Systemic ... bartonella) • Rheum/AI ... , Sarcoidosis, SLE ... insufficiency, Chronic