12 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... Cryoglobulinemia Renal-centered ... #Differential #Diagnosis ... #hematology #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... constitutional symptoms ... hyperCalcemia, Renal ... #Significance #hematology ... #diagnosis #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Reactive: - Systemic ... Lupus Erythematosus ... Lymphocytes) - Monoclonal ... #Oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... dL the ULN R - Renal ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... #SLE #systemic ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... ; vaccinations Renal ... Complications #diagnosis ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... : • Symptoms limited ... #Systemic #Lupus ... Erythematosus #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... refractory disease : monoclonal
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
development of skin symptoms ... ’s syndrome - Lupus ... Leukemia cutis Diagnosis ... Sweet #Syndrome #diagnosis ... #dermatology #oncology