20 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... Cryoglobulinemia Renal-centered ... #Differential #Diagnosis ... #hematology #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Lupus Erythematosus ... Age > 50 • Chronic ... Lymphocytes) - Monoclonal ... #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... constitutional symptoms ... hyperCalcemia, Renal ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... dL the ULN R - Renal ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... #SLE #systemic ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... - CHRONIC CUTANEOUS ... - SEROSITIS - RENAL ... #Rheumatology #SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... months to years) Systemic ... • Evolution: Chronic ... #rheumatology #diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... ; vaccinations Renal ... Complications #diagnosis ... #hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Chronic ... renal failure ... #Secondary #dermatology ... #Differential #Diagnosis