13 results
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... Algorithm Acute ... • Hepatorenal syndromes ... Drugs • Emboli Systemic ... Acute Interstitial Nephritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... APLA/LAC: • Renal ... #Systemic #Lupus ... Erythematosus #Diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... block • Sjogren syndrome ... severe disease Treatment ... diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... nephritis. ... overlap syndromes ... #diagnosis #rheumatology ... #table #ANA
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... inhibitors, hepatorenal syndrome ... Secondary GNs: Due to systemic ... Post-infectious GN, Lupus ... Acute Interstitial Nephritis
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Nephrotic ... syndrome #NailDisorders ... #dermatology #Differential ... #Diagnosis #Algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... nephritis, NPSLE ... life-threatening • Treatment ... #table #rheumatology ... #diagnosis #management
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Algorithm Hypertension ... Glomerulonephritis • Nephritic ... syndromeAKI ... Sympathetic nervous system ... #Algorithm #Causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... #Diagnosis #Management
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... failure, Cirrhosis, Nephrotic ... syndrome) • ADH ... #differential #diagnosis ... #table #sodium