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diagnosis differential rheumatology management algorithm hematology systemic acute aki classification erythematosus nephrology kidneyinjury secondary activation ana anca anesthesia anesthesiology antibodies
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria ... hemolysis • Renal ... nephritis, Class ... nephritis Immunologic ... #SLE #Systemic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... nephritis, NPSLE ... • Immunologic Workup ... Positive in 60-80% of cases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Shrinking lung syndrome ... APLA/LAC: • Renal ... SSA can rule in SLE ... papillomavirus #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... • Immunologic Workup ... Discontinuation of causal ... nephritis, NPSLE ... • Immunologic Workup
Causes of Pleural Effusion - Differential Diagnosis Algorithm Exudative Effusion: - Pulmonary •
Causes of Pleural ... Inflammatory (RA, SLE ... Failure • Renal ... Cirrhosis • Nephrotic ... Syndrome Light's
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
• Hepatorenal syndromes ... IgA, post-strep, lupus ... Acute Interstitial Nephritis ... legionella) • Immune (lupus ... Diagnosis #Algorithm #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... • Interstitial nephritis ... syndrome: troponin ... #Injury #AKI #Workup
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Common causes of ... inhibitors, hepatorenal syndrome ... Post-infectious GN, Lupus ... Acute Interstitial Nephritis ... NephroP #AKI #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Nephrotic ... syndrome #NailDisorders ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #differential #hematology
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