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diagnosis differential rheumatology pathophysiology systemic vasculitis algorithm antibodies arthritis autoantibodies classification complications cord disease disorders laboratory manifestations mimickers msk musculoskeletal
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... erythematosus ( ... erythematosus ( ... @AnnKumfer #Antinuclear
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #Erythematosus ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... #Erythematosus ... autoantibodies #signs ... #symptoms #mimickers
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
: Pathogenesis and ... RA) or systemic lupus ... erythematosus ( ... SLE) Signs / Symptoms ... #Symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
myelitis: Motor and ... disorders (Systemic lupus ... erythematosus, ... Manifestations #diagnosis #neurology ... #symptoms #signs
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus ( ... SLE) - Antinuclear ... • Hepatitis B serology ... C serology testing
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... and signs below ... Spinal abscess: hematogenous ... Behcet disease - SLE ... disorders #diagnosis #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... erythematosus, ... Presentation - Systemic Symptoms ... purpura: strong sign ... SLE) • Urinalysis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... ischemia • Skin: Erythematous ... • Progressive symptoms
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