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diagnosis rheumatology management ana antibodies differential hematology patterns activation acute anca antibody antineutrophil autoantibodies cerebritis cns dermatosis diseases febrile macrophage
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... lupus erythematosus ... Syndrome (SS), ... lupus erythematosus ... (SLE), Systemic
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... block • Sjogren syndrome ... severe disease Treatment ... #Lupus #Erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... (SLE), Systemic
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... overlap syndromes ... autoantibodies #Systemic ... #lupus #erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Lupus Erythematosus ... (SLE) Clinical ... Demyelinating Syndrome ... #Lupus #Erythematosus
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... cases • Sjögren syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Histopathologic criteria ... Treatment: • Corticosteroids
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
for Sweet Syndrome ... onset of tender erythematous ... Excellent response to treatment ... with systemic corticosteroids ... #Dermatology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... (GBS), systemic ... lupus erythematosus ... (SLE), polymyositis ... (LEMS), systemic
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
disorders, including systemic ... lupus erythematosus ... (SLE), Sjögren’ ... in LNs and the systemic ... Hypoalbuminemia Treatment
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