49 results
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Differential Diagnosis Algorithm ... necrolysis - Systemic ... lupus erythematosus ... MucousMembranes #dermatology ... #causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Demyelinating syndromes ... #SLE #systemic ... erythematosus #signs
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic ... Arthritis, Sjögren Syndrome
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Workup: - ANA ... Positive in 60-80% of cases ... #lupus #Systemic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... #rheumatology #
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... is clinically suspected ... overlap syndromes ... #diagnosis #rheumatology ... #table #ANA
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
with Eosinophilia and ... Systemic Signs ... (DRESS Syndrome) ... medication (in this case ... #Dermatology #SkinRash
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
with Eosinophilia and ... Systemic Signs ... (DRESS Syndrome) ... medication (in this case ... #Dermatology #SkinRash
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #differential #hematology