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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Lupus Erythematosus ... Microangiopathies #Systemic ... #Lupus #Erythematosus ... #SLE #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... Usual therapeutic management ... #lupus #Systemic
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... /systemic sclerosis ... @AnnKumfer #Systemic ... #Lupus #Erythematosus ... #rheumatology #management
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
cytoplasmic antibodies; SLE ... , systemic lupus ... Glomerulonephritis #Algorithm
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Differential Diagnosis Algorithm ... Blisters - Primary Dermatologic ... necrolysis - Systemic ... Disease • Systemic ... lupus erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... RheumOnePagers) #Systemic ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have ... Differential #Diagnosis #Algorithm
Relapsing Acute Severe Ulcerative Colitis - Management Algorithm
Loss of Response:
 • (Re)consult Colorectal Surgery
 • Assess
Ulcerative Colitis - Management ... surgery: Fulminant UC ... Toxic Megacolon, Systemic ... and Family • RD ... #Management #Algorithm
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... • Cyanosis Red ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... months to years) Systemic ... Usual therapeutic management ... rheumatology #diagnosis #management