38 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... #SLE #systemic
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... Suggestive of: Lupus ... Suggestive of: Lupus ... Suggestive of systemic ... gabrieltalledop #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... • SLE • Human ... lesions • Discoid lupus ... Sarcoidosis #dermatology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
identification of red-flags ... to exclude dermatologic ... New-onset fever with rash ... sulfa-drug - Skin ... #Rash #Maculopapular
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... , oral ulcers, Lupus ... #lupus #Systemic
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Scaring alopecia • Red ... inflammation on skin ... Malar (butterfly) Rash ... Manifestations #pathophysiology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - with the skin ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Female • Peaks 3rd ... Decade Skin ... #Systemic #Lupus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Disease, PRES Pathophysiology ... RheumOnePagers) #Systemic ... #SLE #CNS #neurology