13 results
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Lupusreference #Antinuclear ... autoantibodies #Systemic ... #rheumatology #table
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... #Lupus #Erythematosus ... #SLE #Gastrointestinal ... Complications #pathophysiology ... #signs #symptoms
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... (SLE), Systemic ... (SLE), Systemic ... Kumfer @AnnKumfer #Antinuclear
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #Lupus #Erythematosus ... Complications #pathophysiology ... #signs #symptoms
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Constitutional symptoms ... constitutional symptoms ... months to years) Systemic ... #table #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... lupus erythematosus ... (SLE) Signs / ... Symptoms: - Lymphocyte ... Sjogrens #Syndrome #Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Scaring alopecia • Red ... #SLE #Mucocutaneous ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... Neuropsychiatric systemic ... : • Symptoms limited ... #Systemic #Lupus
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... - Red blood cell ... lupus erythematosus ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Episcleritis Signs and Symptoms ... development of skin symptoms ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology