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differential rheumatology causes algorithm erythematosus lupus management systemic hemolysis oncology signs symptoms workup activation atlas autoantibodies clinical cutaneous eschar extravascular
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... : • Thrombotic ... syndrome (ST-HUS ... anemia" • HELLP ... #hematology #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... syndrome - Thrombotic ... microangiopathy: Thrombotic ... #hematology #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... RA, SLE, PRV, Chronic ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... uremic syndrome, Thrombotic ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... #Diagnosis #causes ... #classification ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... • Bleeding • Hemolysis ... #MCV #Classification ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... genotypes): SS, SC, SE ... #Anemia #Differential ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... activity is the diagnostic ... result in severe anemia ... anemia Indirect ... #Workup #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #hematology #rheumatology ... #nonpalpable #dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
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