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management hematology erythematosus sle systemic druginduced hus microangiopathy syndrome thrombocytopenia thrombotic ana antinuclear autoantibodies behcet causes cerebritis cns coagulation dic
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... Table • Thrombotic ... Toxin-Mediated HUS (ST-HUS ... TMA - Drug-induced ... Microangiopathy #TMA #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... 5-10d, venous (DVT ... complex → plt activation ... #Management #Treatment ... #Hematology #HemeOnc
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... vasculopathy, thrombosis ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Chronic B-cell activation ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Sepsis • Drug-induced ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
60-70%) & drug-induced ... -15% If SLE is clinically ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... sequestration and activation ... : 33% • Treatment ... #diagnosis #comparison ... #table
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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