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differential causes hematology management pediatrics thrombocytosis b12 celiac ckd cobalamin endocrinology erythematosus fatigue ferritin gastroenterology gastronintestinal hemodialysis incomplete iron kawasaki
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... Structural: Celiac disease ... Tropical sprue, IBD ... #Diagnosis #Algorithm
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis ... Algorithm Normal ... • GH Deficiency ... • IGF-I Deficiency ... Celiac, IBD) •
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... • Iron-deficiency ... anemia unresponsive ... Inflammatory (IBD ... #Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Inflammatory: • IBD ... disorders • Celiac disease ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... restricted diet/deficiency ... fatigue despite disease ... #Algorithm #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Acute hemolysis, deficiency ... anemia, Rebound ... Vasculitides, IBD ... , Celiac disease
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... diarrhea related to IBD ... , celiac disease ... large total body stores ... #diagnosis #management
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... Albumin ≤3.0 g/dL, anemia ... purposes of this algorithm ... effusion, or z scores ... #Diagnosis #Peds
Occult and Lower Gastronintestinal Bleed - Differential Diagnosis Algorithm Occult (Stool + Occult blood and/or iron deficiency
- Differential Diagnosis ... Algorithm Occult ... blood and/or iron deficiency ... anemia) • Colorectal ... , asymptomatic IBD
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Prolidase deficiency ... • Malar rash - spares ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
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