22 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... diagnosis #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
brain, eye, and ear ... Visual or auditory symptoms ... conjunction with symptoms ... diagnosis and treatment ... Systemic lupus erythematosus
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Syndrome (SS), ... Arthritis, Sjögren Syndrome ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Shrinking lung syndrome ... Induced Lupus: • Symptoms ... SSA can rule in SLE ... #Diagnosis #Rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... systemic lupus erythematosus ... (SLE) Signs / ... - Decreased tear
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Pulmonary ... , Behçet's syndrome ... Inflammation of ear ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... pain (20%) Renal disease ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... Systemic Lupus Erythematosus ... (SLE), should have ... other symptoms
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... systemic lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... #Rheumatology