78 results
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
trigger - Direct skin ... 50% of patients Skin ... - Ice cube test ... , TempTest test ... Urticaria #diagnosis #rheumatology
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
for Celiac Disease ... patients with celiac disease ... value for celiac disease ... Reflects response to treatment ... #Diagnosis #Workup
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... with more severe disease ... Associated with skin ... Treatment: • ... Summary #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... K), H. pylori test ... thyroid function test ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... • Nonmalignant hematologic ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bruising • Skin ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... (this is a skin ... prick test that ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... symptoms (eg, skin ... Differential #diagnosis #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... LcSSc) - distal skin ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... autoinflammatory diseases ... diagnosis #management #treatment ... #rheumatology