16 results
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
in (Antiphospholipid ... Syndrome) APS ... - Arterial Thrombosis ... #Syndrome #APS ... #rheumatology #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
vs Arterial Thrombosis ... • Nephrotic Syndrome ... THROMBOSIS Arterial ... Malignancy - Antiphospholipid ... pathophysiology #hematology
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid ... Syndrome (APS) ... clots can form in arteries ... or small-vessel thrombosis ... #Syndrome #APS
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
Syndrome (APS) ... previous history of thrombosis ... Previous history thrombotic ... APS (arterial or ... #Syndrome #APS
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Hypercoagulable State Arterial ... risk actor for arterial ... thrombosis) Venous ... - No other workup ... Hypercoagulable #Workup
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... /HUS indicates thrombotic ... hemolytic uremic syndrome ... thrombocytopenia, Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
RA, Sjogren's), antiphospholipid ... syndrome, atheroembolic ... 90%), subacute bacterial ... #differential #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
HCV, EBV, CMV - Bacterial ... Autoimmune: SLE, RA, antiphospholipid ... syndrome - Pregnancy ... Diagnosis #Framework #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Hypercoagulable Workup ... clinical episodes of arterial ... or small-vessel thrombosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
necrosis) - Thrombosis ... (Thrombotic vasculopathy ... to medium-sized arteries ... HUS and HIT • Antiphospholipid ... syndrome • Warfarin-induced