28 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... sicklecells #sickle #hematology ... #anemia #clinical
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... Differential Diagnosis Table ... Cold Agglutinin Disease ... Autoimmune #Hemolytic #Anemia ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
disorders • Celiac disease ... Non malignant hematologic ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... telomeropathy Cancer ... and Autoimmune Diseases ... Differential #Diagnosis #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic Anemia ... (AIHA) Treatment ... esp if severe disease ... #AIHA #Treatment ... #management #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
particular degree of anemia ... Index < 2: • Anemia ... Chronic kidney disease ... infiltration (e.g. cancer ... Production #Index #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g. celiac disease ... Anticoagulant Medications ... Advanced Liver Disease ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
thrombocythemia), Autoimmune disease ... adsorption onto cancer ... Diagnosis #Management #treatment ... #hematology #differential