19 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... (MCTD), Drug-induced ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Systemic lupus erythematosus ... (MCTD), Drug-induced ... ANA #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Systemic lupus erythematosus ... Anti-histone (in drug-induced ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... SLE-Related Auto-Antibodies ... Lupus Mimickers: Drug-induced ... sclerosis, Still's disease ... #differential #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Anti-histone - Drug-induced ... #diagnosis #table ... #rheumatology # ... antibodies
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... extremities Drug ... 1, SCL-70, RNP antibodies ... • Antihistone: Drug ... #Diagnosis #Rheumatology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the ... Even with macular disease ... smfarmhosp_smfh #Drugs ... #COVID19 #Pharmacology ... #Table #Management
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... SLE (60-70%) & drug-induced ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #