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diagnosis management differential erythematosus dermatology systemic syndrome algorithm oncology vasculitis classification druginduced hairloss hemophagocytic hlh joint lymphohistiocytosis pain summary workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Photosensitivity, Alopecia ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin Disease ... : Discoid lupus ... : Lupus erythematosus ... of any comorbid disease ... Scaling, pustules, crusts
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Photosensitivity, Alopecia ... life-threatening • Treatment ... Evolution: Chronic disease ... #table #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Irreversible-biopsy required • Lupus ... Related • Post-infectious ... Secondary to Skin Disease ... • Discoid lupus ... Diagnosis #Algorithm #causes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
parvovirus B19 infection ... Malar rash • SLE ... parvovirus B19 infection ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... (RA), Systemic lupus ... erythematosus (SLE ... rare), Idiopathic Infectious ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... • Specific for SLE ... Treatment: • ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Diagnosis Algorithm Infectious ... Inflammatory • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... and permanent alopecia ... fibromyalgia) • Infections ... • Nonscarring alopecia ... Erythematosus #Diagnosis #Rheumatology
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