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hematology anemia differential algorithm workup babesiosis autoimmune infectiousdiseases management aiha causes clinical fever hemolysis pathology pathophysiology peripheral testing aafp agglutinin
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing in Hemolytic ... Extravascular Hemolysis ... LDH Peripheral smear ... Testing #workup #diagnosis ... #hematology #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... of anemia and hemolysis ... Abnormal peripheral smear ... #Differential #Diagnosis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... reticulocytes • Hemolysis ... C3d • Blood smear ... #Anemia #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... - Differential Diagnosis ... Peripheral blood smear ... Immune mediated hemolysis ... #Differential #Diagnosis
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... or negative - Smear ... C3 positive - Smear ... AIHA #Autoimmune #Hemolytic ... Pathophysiology #diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... and laboratory diagnosis ... Microangiopathic hemolytic ... arrow) Peripheral smear ... Hematology #Pathology #Smear
Babesiosis - Babesia Life Cycle 1) Tick takes a blood meal (sporozoites introduced into host) 2) Trophozie ←→
Babesiosis - Babesia ... into host) 2) Trophozie ... into host) 7) Trophozie ... #Babesiosis #Babesia ... #LifeCycle #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... (oroya fever), babesia ... ARUPConsult @ARUPLabs #Hemolytic ... #Differential #Diagnosis
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Bartonella, Babesia ... udaygulati #Hemolytic ... #Differential #Diagnosis
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic ... • Parasitic- Babesia ... #Autoimmune #Hemolytic ... #Anemia #AIHA #Diagnosis
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