19 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential ... of anemia and hemolysis ... Abnormal peripheral smear ... #Anemias #Differential
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
on smear Glanzmann ... clumping on smear ... on smear, as well ... on smear, Associated ... comparison #table #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential ... Peripheral blood smear ... Immune mediated hemolysis ... #Anemia #Differential
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... Microangiopathic hemolytic ... arrow) Peripheral smear ... other testing (platelet ... Hematology #Pathology #Smear
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... C3d • Blood smear ... : Differential → ... Antibody #Autoimmune #Hemolytic
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... < 1800/uL, • platelet ... acid, peripheral smear ... ↑ Destruction (hemolysis ... #Pancytopenia #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Peripheral Smear ... blood loss, Acute hemolysis ... #Differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... Platelet count ... Peripheral blood smear ... and decreased platelet ... WBC count and differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... with or without platelet ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet ... Disorders - Differential ... peripheral blood smear ... dysplasia on the smear ... #Disorders #Differential