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diagnosis hematology anemia algorithm hemolysis classification extravascular intravascular management oncology thrombocytopenia thrombocytosis aafp agglutinin antibody bruising cirrhosis cold disease disorders
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Abnormal peripheral smear ... : • Autoimmune ... Hemolytic Anemias ... #Anemias #Differential
Anemia - Hemolysis Diagnostic Algorithm Autoimmune hemolytic anemia Microangiopathic hemolytic anemia Probable thalassemia Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... Diagnostic Algorithm Autoimmune ... hemolytic anemia ... hematology #diagnosis #differential ... #workup
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... C3d • Blood smear ... : Differential → ... 2) LOOK FOR a cause ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Peripheral blood smear ... idiopathic, malignancy, autoimmune ... #Anemia #Differential ... Diagnosis #Algorithm #causes
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup
Anemia - Workup and Differential Diagnosis - History, Physical Exam, Labs - Microcytic - Normocytic -
Anemia - Workup ... and Differential ... Macrocytic - Hemolytic ... #Anemia #Workup ... Diagnosis #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... idiopathic) - Autoimmune ... Extravascular #Causes ... #differential #
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Cold AIHA • Alloimmune ... anemia • ... Extravascular #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... elliptocytosis, autoimmune ... #Anemia #Differential ... Diagnosis #Algorithm #workup
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... #Differential #
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