18 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
C3d • Blood smear ... : Differential → ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... • Limited to Kidney ... With associated pulmonary ... #diagnosis #algorithm ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... coagulopathy) • CBC w differential ... Goodpasture's cause ... #differential # ... #treatment
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
Types of Renal Calculi ... amino acids in kidney ... - Antiviral treatment ... #stones #differential ... #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Management Summary Causes ... nephrotoxicity to kidney ... #causes #treatment
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... disequilibrium syndrome • Diagnosis ... Torsemide) • Acute pulmonary ... stones caused by ... Tolvaptan) • Treatment
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Diagnosis Algorithm ... Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... Hypoxia-independent: Post-renal ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... Peripheral blood smear ... WBC count and differential ... the presence of renal ... #Workup #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Bleeding (64%) • Renal ... • Peripheral smear ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The ... before beginning treatment ... output - Acute pulmonary ... #Diagnosis #causes