745 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... distinction has HUGE treatment ... implications : TTP ... and first-line treatment ... confirmatory testing for TTP
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Diagnosis of TTP ... • Distinguish TTP ... HUS) Treatment ... Purpura #management #treatment
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP ... HELLP Syndrome • TTP ... Diagnosis #Algorithm #Causes
Important Respiratory Distress Pearls

#diagnosis #respiratory #distress #NRDS #RDS #TTN #MAS #neonatal #pediatric #adult #respiratory #adverse #effects
distress #NRDS #RDS #TTN ... adverse #effects #pulmonary ... ventilation #algorithm #causes
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
in Anaesthesia Caused ... or iatrogenic causes ... thoracotomy is a better treatment ... of underlying cause ... small volume may cause
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... MALIGNANCY: - TMA: TTP ... HIT - MAHA: TTP
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Microangiopathy: DIC, TTP ... Antibody-mediated: ITP
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Pneumonitis • Treatment ... BrighamChiefs #ILD #Causes ... lung #disease #pulmonary
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Thrombocytopenia: ITP ... • Secondary Causes ... disease - DIC/TTP ... Defects: • DIC, TTP
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... TMA is due to TTP ... compliment-mediated TTP ... TTP is only TMA ... suggests against TTP