16 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... Malar rash ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... phenomenon (20%) Joints ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... anti-synthetase syndrome ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... everywhere) 2) A rash ... 6) An annular rash ... Unexplained fever, when infection ... erythematosus #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders ... arthritis - (Reiter’s syndrome ... within 1 month of infection ... Erythematosus (SLE ... like “butterfly rash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Arthritis: • Joint ... arthropathy • 90% joints ... Erythematosus #Diagnosis #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Bacterial or viral infection ... Heberden's nodes (DIP joints ... Cardiomyopathies - Viral infection ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... involvement 3% SLE-Related ... Other auto-immune, Infectious ... Lupusreference #SLE ... #differential #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE ... ], AOSD) • Infection ... Diagnosis #Management #Hematology ... #Rheumatology