1606 results
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
- Excess free water ... Decreased intake of water ... • No access to water ... GI loss • Watery ... Hypernatremia #Nephrology
Hypernatremia Management Algorithm
Acute vs Chronic
Calculate Losses
 • Current water Deficit
 • Ongoing Free water Losses
 •
Losses • Current water ... • Ongoing Free water ... Ongoing Urinary Water ... Algorithm #treatment #nephrology
Pathophysiology of The Nephron - Electrolyte and Water Exchange

The nephron — electrolyte and water exchange. 
180
Electrolyte and Water ... electrolyte and water ... exchange. 180 L of water ... approximately I L of water ... Pathophysiology #Nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Diagnosis Inadequate water ... Lack of access to water ... Diagnosis #Causes #nephrology
Nephron Physiology
 - Proximal Convoluted Tubule
 - Thick Ascending Limb
 - Distal Convoluted Tubule
 - Ion
Collecting Tubule - Water ... Pathophysiology #Nephrology
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Output > 3L /day Water ... 200 mOsm/kg) • Water ... Algorithm #causes #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
to unreplaced water ... loss (free water ... a clue). 1) ↓ Water ... • Free water ... Treatment #management #nephrology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
#3 - Perform a water ... Algorithm #Sodium #nephrology
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
asymptomatic; water ... Pathophysiology #Nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Hypovolaemia → ADH → water ... Pathophysiology #diagnosis #nephrology