Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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diagnosis differential management rheumatology lupus druginduced ana anemia antibody antinuclear antiphospholipid apls comparison cytoplasmic diarrhea dil disorders emergencies eosinophil eosinophilia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... Differential #diagnosis #hematology
Diarrhea Workup and Management Algorithm in Transplant Patients First Tier Microbiologic-Testing: 1. C. difficile PCR (Stool) 2. CMV qPCR
Diarrhea Workup ... and Management Algorithm ... Ova and Parasite evaluation ... PTLD, GVHD or IBD ... #Diarrhea #Workup
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... • Evolution: ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... Positive in 60-80% of cases ... • Evolution: ... Management #Summary #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... Scl70 (in some cases ... , SjS, CTD-ILD, ... Antinuclear #Antibody #Testing ... differential #diagnosis #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... genotypes): SS, SC, SE ... Differential #Diagnosis #Algorithm ... #workup #hematology ... #testing
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... Better call hematology ... some time, let’s see ... #workup #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... Algorithm INDICATIONS ... maternal chromosomal causes ... #Algorithm #diagnosis ... #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... allopurinol 300 mg BID ... Treat underlying cause
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... • Immunologic Workup ... Discontinuation of causal ... cutaneous-DIL • Evolution ... DrugInduced #Lupus #DIL #rheumatology
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