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Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Sites #Action #Nephron ... #Pharmacology # ... Nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Ketoacidosis: Diabetic ... oxoproline) • Renal ... Renal acidosis ... Generalized distal nephron ... #nephrology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes ... or neurogenic diabetes ... Acquired - Primary renal ... uropathy, Metabolic causes ... Classification #Types #Nephrology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... vasopressin control #Nephron ... Pathophysiology #Tubules #Table ... #Pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Kidney stones caused ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... receptor Distal renal ... ATPase Nephrogenic diabetes ... Defects #Kidney #Nephrology ... #Differential #Table
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... Correction of diabetic ... (steatorrhea) Renal ... Tubulointerstitial renal ... medications #drugs #pharmacology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Correction of diabetic ... steatorrhea) • Renal ... Tubulointerstitial renal ... differential #diagnosis #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... (treatment of diabetic ... Villous adenoma Renal ... chewing tobacco, Renal ... differential #diagnosis #nephrology
Medications Used in the Abortive Treatment of Ongoing Seizure Activity in the Emergency Department

INITIAL THERAPY
 -
Phenytoin - May cause ... #Medications #Neurology ... #Pharmacology # ... Dosing #Table