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Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of ... 8.0 mg/dL • Potassium ... Intravenous fluids • Renal ... hydroxide • Hyperkalemia ... Syndrome #TLS #diagnosis
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Classification, ... Differential Diagnosis ... Glucocorticoid deficit - Hypokalemia ... Drugs - SIADH Renal ... #Table #Causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
oxoproline) • Renal ... Renal acidosis ... Potassium-sparing ... #differential #diagnosis ... #causes #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... - Differential Diagnosis ... Algorithm Hypovolemia ... #Algorithm #Causes ... #nephrology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Acquired - Primary renal ... uropathy, Metabolic causes ... (e.g., hypokalemia ... #Types #Nephrology ... #Diagnosis #Differential
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Villous adenoma Renal ... chewing tobacco, Renal ... #Causes #differential ... #diagnosis #nephrology
Causes of Hyperkalemia
Pseudohyperkalemia
 - Tourniquet use
 - Hemolysis (in vitro)
 - Leukocytosis
 - Thrombocytosis
Intra- to extracellular
Causes of Hyperkalemia ... excretion - Renal ... Selective defect in renal ... acidosis) #Hyperkalemia ... #Causes #diagnosis
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... (steatorrhea) Renal ... osmotic diuresis - Potassium ... #diagnosis #differential ... medications #drugs #pharmacology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... Hypodipsia - Renal ... #Features #Diagnosis ... #Comparison #Table ... #Nephrology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... steatorrhea) • Renal ... osmotic diuresis, Potassium ... #differential #diagnosis ... #nephrology #magnesium