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Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP DIURETICS ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... thiazide-like diuretics ... , Osmotic diuresis ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... Kidney stones caused ... #Nephrology #Pharmacology ... #Medications #Table
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Renal losses, Diuretic ... Ketonuria, Osmotic diuresis ... Diagnosis #Algorithm #Causes ... #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... Saline or osmotic diuresis ... Drugs: - Loop diuretics ... Hypomagnesemia #Causes ... #differential #medications
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Saline or osmotic diuresis ... • Drugs: Loop diuretics ... Hypomagnesemia #Causes ... differential #diagnosis #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Metabolic Acidosis Causes ... and chronic) Causes ... Potassium-sparing diuretics ... #nephrology
Causes of Constipation in Adults
Most common
 - Inadequate fiber or fluid intake
 - Poor bowel habits
Systemic
Causes of Constipation ... porphyria - Neurologic ... autonomic neuropathy Medications ... - Opioids - Diuretics ... #Constipation #Causes
Medications Used in the Abortive Treatment of Ongoing Seizure Activity in the Emergency Department

INITIAL THERAPY
 -
Medications Used ... Phenytoin - May cause ... Abortive #Seizure #Medications ... #Neurology #Pharmacology