Manual of Medicine @ManualOfMedicine
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Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... organic acids and bases ... acid and most diuretics ... #Pathophysiology ... #Tubules #Table
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... , nasogastric suction ... , Osmotic diuresis ... #Hypokalemia #Causes ... #differential #
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... - Differential ... Diagnosis Algorithm ... Renal losses, Diuretic ... #Causes #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... - Nasogastric suction ... Drugs: - Loop diuretics ... Hypomagnesemia #Causes ... #diagnosis #differential
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Shock #Shock #Pathophysiology ... #differential # ... diagnosis #algorithm ... #causes
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Classification, Differential ... hyponatremia - Diuretics ... Classification #Differential ... #Diagnosis #Table ... #Causes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... Kidney stones caused ... the Nonspecific Cation ... #Medications #Table
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... Diagnosis Algorithm ... #causes #potassium ... #low #pathophysiology
Unmeasured Anions Associated with an Elevated Anion Gap and Metabolic Acidosis

#Unmeasured #Anions #Gap #Metabolic #Acidosis #Diagnosis
with an Elevated Anion ... Diagnosis #Nephrology #Table ... #Differential # ... Causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Metabolic Acidosis Causes ... and chronic) Causes ... Potassium-sparing diuretics ... Metabolic #Acidosis #differential