Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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management oncology differential monoclonal gammopathy hemophagocytic hlh lymphohistiocytosis capillary chronic clarksons cll complications dress eosinophils erythematosus gammopathies hemeonc hes hypereosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... than 1500 and clinical ... Secondary Causes ... #diagnosis #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... capillary leak syndrome ... Ig deposition disease ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management Summary ... old, ~10,000 new cases ... #Management #treatment ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... #Gammopathies #MGUS ... #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... : symptomatic treatment ... • Severe disease ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... rituximab (in clinical ... Complications #diagnosis ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Treatment: • ... #summary #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
- OnePager Summary ... life-threatening diseases ... o infection • Echocardiogram ... Goodpasture's cause ... #management #treatment
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) - Summary ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
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