Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP ... #Thrombocytopenia ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... Microangiopathy #thrombocytopenic ... HemolyticUremicSyndrome #HUS #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... of child 3) TTP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... Microangiopathy: DIC, TTP ... antiphospholipid syndrome - Pregnancy ... #Framework #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
triad of MAHA + thrombocytopenia ... TMA is due to TTP ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... usually IgG) (e.g. lupus ... #hematology #anemia
Peripartum Cardiomyopathy - Summary
1. Definition
 β€’ Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... during Delivery β€’ Stable ... auto-transfusion and relief ... should be done on diagnosis ... Cardiomyopathy #diagnosis