Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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diagnosis management clinical dermatology differential comparison anemia hemophagocytic hlh lupus lymphohistiocytosis oncology summary vasculitis adultonset associations autoantibodies complications diseases erythematosus
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... Drugs (Beta lactam antibiotics ... spherocytosis) • Infections ... differential #diagnosis #hematology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... PSS: Sjogren syndrome ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... #diagnosis #table ... #rheumatology #
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
Non-HCV infectious ... neuropathy Treatment ... Specific anti-infectious ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
: • Recurrent infections ... megaloblastic anemia Treatment ... (transfusions, antibiotics ... diagnosis #management #treatment ... #hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... #Syndrome #Treatment ... #pharmacology #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Diaqnoses: • Infectious ... autoinflammatory diseases ... diagnosis #management #treatment ... #rheumatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
malnutrition, Antibiotics ... Malabsorption (e.g. celiac disease ... Advanced Liver Disease ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... : • Infection ... rapidly, and empiric antibiotic ... #hematology
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