Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... (AFLP) Three syndromes ... child * Severe cases ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
Causes of Thrombocytosis ... Thrombocytosis): β€’ Acute infection ... Post-splenectomy Primary ... Myelodysplastic syndrome ... #hematology #secondary
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... soles in 50% of cases ... and nephrotic syndrome ... to asymptomatic infection ... roots, causing a syndrome
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... There are primary ... and secondary TMA ... cancer, transplant, infection ... , pregnancy, & malignant
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 β€’ Direct lesion contact during sex is responsible
1) Primary Syphilis ... responsible for most cases ... . 2) Secondary ... Albuminuria, nephrotic syndrome ... β€’ Primary, secondary
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... β€’ Parasitic infections ... 3rd pass = Primary ... cell activation syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    β€’ Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... Primary HLH: - ... transplantation Secondary ... associated with infection ... #management #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 β€’ Persistent CD4 T-cell lymphopenia
 β€’
NO underlying primary ... or secondary immune ... chemotherapy) β€’ Genetic syndromes ... myelodysplasia) β€’ Infections ... #Differential #Causes