Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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diagnosis hematology differential thrombocytopenia aflp management obstetrics stages syphilis ttphus allergy anemia cd4 extravascular framework hemolysis hemolytic hemophagocytic hlh hus
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... (AFLP) Three syndromes ... child * Severe cases ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Three syndromes ... child * Severe cases ... #TTPHUS #HELLP ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute infection ... Post-splenectomy Primary ... Myelodysplastic syndrome ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... coagulation (DIC) - HELLP ... syndrome - ... Hemolytic uremic syndrome ... usually IgM) (e.g. primary
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... infiltration: malignancy, infection ... antiphospholipid syndrome ... - Pregnancy: HELLP ... Diagnosis #Framework #hematology
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
Without treatment ... soles in 50% of cases ... and nephrotic syndrome ... to asymptomatic infection ... roots, causing a syndrome
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... There are primary ... and secondary TMA ... cancer, transplant, infection ... , pregnancy, & malignant
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
1) Primary Syphilis ... responsible for most cases ... . 2) Secondary ... Albuminuria, nephrotic syndrome ... • Primary, secondary
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... • Parasitic infections ... 3rd pass = Primary ... cell activation syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... Primary HLH: - ... transplantation Secondary ... associated with infection ... #management #hematology
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