Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 β€’ AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... Injury? ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... Alcoholic cirrhosis, Portal ... #LFTs #transaminitis ... #differential #
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 β€’ NAFLD
 β€’ Cirrhosis
 β€’
Tests (LFTs) - ... Differential Diagnosis ... injury) β€’ Ischemic ... Function #Tests #LFTs ... #Differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury β†’ liver test abnormalities without evidence of liver
Injury - Differential ... Injury β†’ liver ... Injury Differential ... #Injury #Differential ... Transaminitis #LFTs
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... , NOT in bone Total ... hepatocellular injury ... Function #Tests #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 β€’ Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... #differential #
Lelli's Test (Lever Sign) for ACL Injury

A fist is placed under the proximal 3rd of the
Lelli's Test (Lever ... Sign) for ACL Injury ... Normal on the right ... #Sign #ACL #Injury ... physicalexam #sports #msk
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Appearance of Liver Lesions on Various Imaging Modalities
 β€’ Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... Contrast Enhanced Ultrasound ... , Metastasis #Liver ... Lesions #Hepatic #Ultrasound ... POCUS #radiology #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... AST): β€’ US - Normal ... Burak @kwburak #LFTs
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
Portal venous gas ... on hepatic ultrasound ... reflection on the differential ... #venousgas #ultrasound ... #hepatology #liver
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