The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive ... included in DSM 5 criteria ... MajorDepressiveDisorder #Depression ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
Mnemonic: CORRUPT ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic ... #CORRUPT
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #signs #psychiatry ... #criteria
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
Personality Disorder (SPD ... familiarity SPD ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
Pathogenesis and Symptoms ... cause the Positive Symptoms ... cause Negative Symptoms ... Diminished emotional expression ... #signs #psychiatry
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Personality Disorder (AVPD ... or inferior #AVPD ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
clinical findings Symptoms ... DSM-V) - Two Major Depressive ... season at work) Symptoms ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
maintain this state Depressive ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... the above with symptoms ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic