The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs symptoms pharmacology sideeffects anorexianervosa bulimianervosa etoh inhibitors majordepressivedisorder mooddisorders serotonin addiction adhd alcohol alcoholusedisorder anticonvulsants anxiety attentiondeficithyperactivedisorder benzodiazepine
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... symptoms #signs #psychiatry
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Serotonin #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
decr intake -> Withdrawal ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... symptoms #signs #psychiatry ... #criteria
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to use EtOH • Withdrawal ... AlcoholUseDisorder #EtOH #Pathophysiology ... Signs #Symptoms #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
mood - Incr withdrawal ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... Note: Opioid withdrawal ... combined with withdrawal ... #Opiate #Pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Addictions: Pathogenesis Mesolimbic Dopaminergic Pathway: • Dopaminergic neurons in Ventral Tegmental Area (VTA) in midbrain under continuous
Tolerance and Withdrawal ... Drug #Addiction #Pathophysiology ... #Psychiatry #Mesolimbic
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