The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... and Complications ... #PelvicRing #Fractures ... Orthopedics #MSK #diagnosis ... #complications
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... bamboo spine) -> Fracture ... minor trauma #AnkylosingSpondylitis ... pathophysiology #diagnosis ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... onto lateral hip Signs ... /Symptoms/Complications ... #msk #diagnosis ... pathophysiology #signs
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
becomes more severe Signs ... abscess • High grade ... Otalgia (Ear Pain) fades ... pathophysiology #symptoms #signs ... #diagnosis
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... pathophysiology #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Acne • Coarse features ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... / Behavioural Features ... Symptoms related to complications ... pathophysiology #diagnosis ... #signs #symptoms
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... highest mortality rates ... pathophysiology #diagnosis ... #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
lung fibrosis #AnkylosingSpondylitis ... Manifestations #Complications ... pathophysiology #diagnosis ... #signs #symptoms