The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology complications psychiatry lupus sle adhesivecapsulitis alcohol alcoholusedisorder caudaequina cecs chronicexertional compartmentsyndrome erythematosus extraarticular frozenshoulder gait henochscholeinpurpura hsp iga lfcn
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to effects of EtOH ... • Withdrawal symptoms ... , tachycardia, nausea ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
sensory • Before diagnosis ... MeralgiaParesthetica #MSK ... pathophysiology #differential ... #diagnosis #signs ... #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis ... #symptoms #signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... periumbilical region), nausea ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... Sores, scars, calluses ... inducing vomiting #BulimiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... inflammation tends to cause ... pathophysiology #signs ... #symptoms #diagnosis
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