The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
Giant Cell Arteritis ... Weight Loss #Temporal ... PolymyalgiaRheumatica #CranialArteritis ... Signs #Symptoms #Diagnosis ... #Vasculitis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... ) Arteritis: Pathogenesis ... palpation - Vasculitic ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Giant Cell (Temporal ... ) Arteritis: Clinical ... #Arteritis #Complications ... Signs #Symptoms #diagnosis ... #Vasculitis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Posterior hip ... wall • Anterior hip ... impact onto lateral hip ... weight-bear • Arthritic ... Fractures #msk #diagnosis
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathology of the Hip ... • Arthritis ... • Congenital hip ... Slipped capital femoral ... symptoms #signs #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Osteonecrosis Esp ... . humeral and femoral ... signs #symptoms #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Arthralgia's (common), arthritis ... and ankles) #HSP ... #IgA #Vasculitis ... Pathophysiology #Diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... Inflammation of skin (esp ... blood vessels (vasculitis ... blood to limbs (esp ... signs #symptoms #diagnosis