The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... #Syndromes #diagnosis ... pathophysiology #signs ... symptoms #msk #orthopedics ... #neurology
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... spinal cord - Signs ... Ataxia (early sign ... #Myelopathy #diagnosis ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... onto lateral hip Signs ... Fractures #msk #diagnosis ... pathophysiology #signs ... #symptoms #orthopedics
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
cells -> Tissue injury ... Pancarditis and valvular injury ... pathophysiology #diagnosis ... #signs #symptoms
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Typically "inside out" injury ... Open #Fractures #Diagnosis ... Complications #MSK #Orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk #orthopedics
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... (uncommonly injured ... PTFL is rarely injured ... #Sports #MSK #orthopedics ... Grading #Grades #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
#Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics