The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms msk complications fractures lupus psychiatry sle acquired avascularnecrosis bonestrength dermatomyositis disorders disruptors dm erythematosus extraarticular femoralhead femur
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... periumbilical region), nausea ... and ankles) #HSP ... #IgA #Vasculitis ... Pathophysiology #Diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
• Posterior hip ... wall • Anterior hip ... impact onto lateral hip ... Fractures #msk #diagnosis ... signs #symptoms #orthopedics
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Inflammation of skin (esp ... blood vessels (vasculitis ... blood to limbs (esp ... inflammation tends to cause ... signs #symptoms #diagnosis
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Pathology of the Hip ... • Congenital hip ... Iatrogenic • Hip ... pathophysiology #causes ... symptoms #signs #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Subjective Tinnitus: Pathogenesis and clinical findings Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... pathophysiology #differential ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Osteonecrosis Esp ... Myopathy (Also caused ... signs #symptoms #diagnosis
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... Pathophysiology #Diagnosis ... Signs #Symptoms #Vasculitis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
primarily deltoids and hip ... Polymyositis #PM #Diagnosis ... Signs #Symptoms #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis
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