The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
Post-Traumatic Stress Disorder ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Pathogenesis of Anxiety Disorders

Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
Pathogenesis of Anxiety Disorders ... Anxiety Disorders ... ) #Anxiety #Disorders ... #Pathophysiology ... #diagnosis #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive Disorder ... Seasonal Affective Disorder ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
relapse of bipolar disorder ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... behaviours #Bipolar #Disorder ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... AlcoholUseDisorder #EtOH #Pathophysiology ... Signs #Symptoms #Psychiatry
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Pathogenesis • Bipolar Disorder ... Secondary #Causes #Differential ... #Diagnosis #Pathophysiology ... #Psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
Deficit Hyperactive Disorder ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
psychological disorder ... and rigidity Endocrinologic ... #Dysfunction #Pathophysiology
Major Depressive Disorder: Complications
 • Recurrent Depressive Episodes
 • Early parenthood
 • Social isolation and interpersonal
Major Depressive Disorder ... dependence • Anxiety Disorder ... Complications #Pathophysiology ... #Psychiatry