The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... Dizziness - Nausea ... #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... SerotoninNorepinephrine #Inhibitors ... #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... out of cells may cause ... #pathophysiology ... #endocrinology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... MoodDisorders #Diagnosis ... #Pathophysiology ... Signs #Symptoms #Psychiatry
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Overproduction #diagnosis ... signs #symptoms #endocrinology ... #pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
tubules - ACE-inhibitors ... Incr Breakdown of DNA ... Release of purine bases ... Hyperuricemia #Pathophysiology
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
is thought to cause ... is thought to cause ... Schizophrenia #pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... their turn • Causes ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
circuitry -> Decreased Inhibitory ... Manic #Secondary #Causes ... #Differential #Diagnosis ... #Pathophysiology ... #Psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, tachycardia, nausea ... AlcoholUseDisorder #EtOH #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Psychiatry