The Calgary Guide to Understanding Disease @TheCalgaryGuide
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menstrualcycle ovariancycle diagnosis feedbackloop signs symptoms comparison dysfunction follicularphase gh glftap glucocorticoids gravesdisease growthhormone hpoa hyperthyroidism hypothalamicpituitary lutealphase macroadenoma masseffects
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile ... to achieve an erection ... and rigidity Endocrinologic ... #Dysfunction #Pathophysiology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
The Hypothalamic-Pituitary-Ovarian ... hypothalamus and anterior pituitary ... MenstrualCycle #pathophysiology ... HypothalamicPituitary #endocrinology ... #feedback
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
sudden +++ positive feedback ... on the anterior pituitary ... negative to positive feedback ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Feedback Loop: Prolactin ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
- FSH from pituitary ... - LH from pituitary ... LH release from pituitary ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
• Negative feedback ... on hypothalamus/pituitary ... #Osteoporosis #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Hyperthyroidism #endocrinology ... #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
GravesDisease #pathophysiology ... #endocin #endocrinology
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