The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Pathogenesis of Anxiety Disorders

Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... acid (GABA) #Anxiety ... #Disorders #Pathophysiology ... #diagnosis #psychiatry
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, tachycardia, nausea ... , seizure, and anxiety ... AlcoholUseDisorder #EtOH #Pathophysiology ... Signs #Symptoms #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
partum onset) - Anxiety ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Subjective Tinnitus: Pathogenesis and clinical findings
Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... #pathophysiology ... #differential #
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
- Incr guilt, anxiety ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... signs #symptoms #endocrinology ... #pathophysiology
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
sweating, trembling, nausea ... carrying anti-anxiety ... Anticipatory Anxiety ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry